San Domenico Maggiore is a church in Naples, southern Italy, located in the square with the same name. The square is one of the most interesting in Naples and is on the street popularly called "Spaccanapoli" (namely via Benedetto Croce at this particular section of its considerable length) in the historic center of Naples. It was one of the three main east-west streets of the original Greek city of Neapolis.
In the center of the square is an obelisk—a so-called "plague column"—topped by a statue of Saint Dominic, founder of the Dominican Order, erected after the plague of 1656. The original designer of the spire was the Neapolitan architect Cosimo Fanzago. Construction on the spire was started after the plague of 1656 and was finally finished in 1737 under Charles III, the first Bourbon monarch of Naples.
The Church of San Domenico Maggiore incorporates a smaller, original church built on this site in the 10th century, San Michele Arcangelo a Morfisa.
Charles II of Naples began the rebuilding that produced the new Church of San Domenico Maggiore. The work was done between 1283 and 1324, but the church has undergone modifications over the centuries, including one in 1670 that recast the structure in the style of the Baroque. In the 19th century, however, the church was restored to its original Gothic design.
The monastery annexed to the church has been the home of prominent names in the history of religion and philosophy. It was the original seat of the University of Naples, where Thomas Aquinas, a former monk at San Domenico Maggiore, returned to teach theology in 1272. As well, the philosopher monk, Giordano Bruno, lived here.
Artistically, the most notable feature are the frescoes by Pietro Cavallini in the Brancaccio Chapel (1309), depicting Stories of St. John the Evangelist, Crucifixion, Stories of Magdalene and the Apostles Peter, Paul and Andrew. A 13th century crucifix traditionally spoke to Thomas Aquinas. The sacristy houses a series of 45 sepulchres of members of the royal Aragonese family, including that of King Ferdinand I.